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Self-assembly of Filamentous Amelogenin Requires Calcium and Phosphate: From Dimers via Nanoribbons to Fibrils

Enamel matrix self-assembly has long been suggested as the driving force behind aligned nanofibrous hydroxyapatite formation. We tested if amelogenin, the main enamel matrix protein, can self-assemble into ribbon-like structures in physiologic solutions. Ribbons 17nm wide were observed to grow sever...

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Detalhes bibliográficos
Main Authors: Martinez-Avila, Olga, Wu, Shenping, Kim, Seung Joong, Cheng, Yifan, Khan, Feroz, Samudrala, Ram, Sali, Andrej, Horst, Jeremy A., Habelitz, Stefan
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3496023/
https://ncbi.nlm.nih.gov/pubmed/22974364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bm300942c
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