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Structure of an actively exchanging complex between carboxypeptidase A and a substrate analogue.

An x-ray diffraction study at 2.8 A resolution has yielded the structure of a complex between bovine carboxypeptidase A (peptidyl-L-amino-acid hydrolase, EC 3.4.17.1) and (-)-2-benzyl-3-p-methoxybenzoylpropionic acid. This substrate is an analogue of N-(p-methoxy)-benzoylphenylalanine, in which the...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Rees, D C, Honzatko, R B, Lipscomb, W N
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1980
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC349600/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6932021/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.77.6.3288
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