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Coding capacity of a 35 percent fragment of the polyoma virus genome is sufficient to initiate and maintain cellular transformation.

Rat-1 cells were transfected with the restriction enzyme fragment of polyoma virus DNA that extends clockwise from the Bcl I site ((65.4 map units) to the EcoRI site (0/100 map units). Six transformed cell lines were obtained and one of them (BE-1) has been investigated in detail. The viral DNA that...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Novak, U, Dilworth, S M, Griffin, B E
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 1980
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC349598/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6251451/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.77.6.3278
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