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Inhibition of 5′-UTR RNA Conformational Switching in HIV-1 Using Antisense PNAs
BACKGROUND: The genome of retroviruses, including HIV-1, is packaged as two homologous (+) strand RNA molecules, noncovalently associated close to their 5′-end in a region called dimer linkage structure (DLS). Retroviral HIV-1 genomic RNAs dimerize through complex interactions between dimerization i...
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| Hoofdauteurs: | , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Public Library of Science
2012
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3495914/ https://ncbi.nlm.nih.gov/pubmed/23152893 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0049310 |
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