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Necdin modulates proliferative cell survival of human cells in response to radiation-induced genotoxic stress

BACKGROUND: The finite replicative lifespan of cells, termed cellular senescence, has been proposed as a protective mechanism against the proliferation of oncogenically damaged cells, that fuel cancer. This concept is further supported by the induction of premature senescence, a process which is act...

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Detalhes bibliográficos
Main Authors: Lafontaine, Julie, Tchakarska, Guergana, Rodier, Francis, Mes-Masson, Anne-Marie
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3495902/
https://ncbi.nlm.nih.gov/pubmed/22691188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-12-234
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