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The ablation of EZH2 uncovers its crucial role in rhabdomyosarcoma formation
Rhabdomyosarcoma (RMS) is a pediatric tumor that arises from muscle precursor cells. RMS cells express several markers of early myogenic differentiation, but they fail to complete both differentiation program and cell cycle arrest, resulting in uncontrolled proliferation and incomplete myogenesis. P...
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Autors principals: | , , , , |
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Format: | Artigo |
Idioma: | Inglês |
Publicat: |
Landes Bioscience
2012
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Matèries: | |
Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3495825/ https://ncbi.nlm.nih.gov/pubmed/22983009 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.22025 |
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