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The ablation of EZH2 uncovers its crucial role in rhabdomyosarcoma formation

Rhabdomyosarcoma (RMS) is a pediatric tumor that arises from muscle precursor cells. RMS cells express several markers of early myogenic differentiation, but they fail to complete both differentiation program and cell cycle arrest, resulting in uncontrolled proliferation and incomplete myogenesis. P...

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Autors principals: Marchesi, Irene, Fiorentino, Francesco Paolo, Rizzolio, Flavio, Giordano, Antonio, Bagella, Luigi
Format: Artigo
Idioma:Inglês
Publicat: Landes Bioscience 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3495825/
https://ncbi.nlm.nih.gov/pubmed/22983009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.22025
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