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End-on microtubule-dynein interactions and pulling-based positioning of microtubule organizing centers

During important cellular processes such as centrosome and spindle positioning, dynein at the cortex interacts with dynamic microtubules in an apparent “end-on” fashion. It is well-established that dynein can generate forces by moving laterally along the microtubule lattice, but much less is known a...

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Hlavní autoři: Laan, Liedewij, Roth, Sophie, Dogterom, Marileen
Médium: Artigo
Jazyk:Inglês
Vydáno: Landes Bioscience 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3495818/
https://ncbi.nlm.nih.gov/pubmed/22895049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.21753
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