Longitudinal Study of Mammary Epithelial and Fibroblast Co-Cultures Using Optical Coherence Tomography Reveals Morphological Hallmarks of Pre-Malignancy

The human mammary gland is a complex and heterogeneous organ, where the interactions between mammary epithelial cells (MEC) and stromal fibroblasts are known to regulate normal biology and tumorigenesis. We aimed to longitudinally evaluate morphology and size of organoids in 3D co-cultures of normal...

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Bibliographic Details
Main Authors: Chhetri, Raghav K., Phillips, Zachary F., Troester, Melissa A., Oldenburg, Amy L.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2012
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3495770/
https://ncbi.nlm.nih.gov/pubmed/23152864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0049148
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