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MicroRNAs, wild-type and mutant p53: More questions than answers

The tumor suppressor p53 is a sequence-specific transcription factor that activates the expression of genes involved in apoptosis, cell cycle arrest and senescence. p53 can also inhibit gene expression and this effect is partly mediated by inducing several microRNAs (miRNAs). MiRNAs have emerged as...

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Détails bibliographiques
Auteurs principaux: Jones, Matthew Fletcher, Lal, Ashish
Format: Artigo
Langue:Inglês
Publié: Landes Bioscience 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3495745/
https://ncbi.nlm.nih.gov/pubmed/22664917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/rna.20146
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