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Architecture and regulation of negative-strand viral enzymatic machinery

Negative-strand (NS) RNA viruses initiate infection with a unique polymerase complex that mediates both mRNA transcription and subsequent genomic RNA replication. For nearly all NS RNA viruses, distinct enzymatic domains catalyzing RNA polymerization and multiple steps of 5′ mRNA cap formation are c...

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Detalhes bibliográficos
Main Authors: Kranzusch, Philip J., Whelan, Sean P.J.
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3495737/
https://ncbi.nlm.nih.gov/pubmed/22767259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/rna.20345
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