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Medulla oblongata transcriptome changes during presymptomatic natural scrapie and their association with prion-related lesions

BACKGROUND: The pathogenesis of natural scrapie and other prion diseases is still poorly understood. Determining the variations in the transcriptome in the early phases of the disease might clarify some of the molecular mechanisms of the prion-induced pathology and allow for the development of new b...

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Detalhes bibliográficos
Main Authors: Filali, Hicham, Martin-Burriel, Inmaculada, Harders, Frank, Varona, Luis, Serrano, Carmen, Acín, Cristina, Badiola, Juan J, Bossers, Alex, Bolea, Rosa
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3495657/
https://ncbi.nlm.nih.gov/pubmed/22897917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-13-399
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