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Comparison of total and cytoplasmic mRNA reveals global regulation by nuclear retention and miRNAs

BACKGROUND: The majority of published gene-expression studies have used RNA isolated from whole cells, overlooking the potential impact of including nuclear transcriptome in the analyses. In this study, mRNA fractions from the cytoplasm and from whole cells (total RNA) were prepared from three human...

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Dettagli Bibliografici
Autori principali: Solnestam, Beata Werne, Stranneheim, Henrik, Hällman, Jimmie, Käller, Max, Lundberg, Emma, Lundeberg, Joakim, Akan, Pelin
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3495644/
https://ncbi.nlm.nih.gov/pubmed/23110385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-13-574
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