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Palladium-Catalyzed Diastereo- and Enantioselective Formal [3+2]-Cycloadditions of Substituted Vinylcyclopropanes

We describe a palladium-catalyzed diastereo- and enantioselective formal [3+2]-cycloaddition between substituted vinyl-cyclopropanes and electron deficient olefins in the form of azlactone- and Meldrum’s acid alkylidenes to give highly-substituted cyclo-pentane products. By modulation of the electro...

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Bibliographic Details
Main Authors: Trost, Barry M., Morris, Patrick J., Sprague, Simon J.
Format: Artigo
Language:Inglês
Published: 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3495600/
https://ncbi.nlm.nih.gov/pubmed/23030714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja309003x
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