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Sequential C(sp3)-H arylation and olefination: total synthesis of the proposed structure of pipercyclobutanamide A

HIP TO BE SQUARE: A strategy for assembling tetrasubstituted cyclobutanes is reported in the context of a short, protecting-group-free synthesis of the proposed structure of pipercyclobutanamide A. The route features sequential C–H functionalizations on an unactivated cyclobutane wherein C–C bonds t...

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Detalhes bibliográficos
Main Authors: Gutekunst, Will R., Gianatassio, Ryan, Baran, Phil S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3495593/
https://ncbi.nlm.nih.gov/pubmed/22715157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201203897
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