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Structural Considerations for Chromatin State Models with Transcription as a Functional Readout

Lacking from the rapidly evolving field of chromatin regulation is a discrete model of chromatin states. We propose that each state in such a model should meet two conditions: a structural component and a quantifiable effect on transcription. The practical benefits to the field of a model with great...

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Autors principals: Chen, Haodong, Monte, Emma, Parvatiyar, Michelle S., Rosa-Garrido, Manuel, Franklin, Sarah, Vondriska, Thomas M.
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3495570/
https://ncbi.nlm.nih.gov/pubmed/22940112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2012.08.018
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