TGFβ-Inducible Early Gene-1 (TIEG1) Mutations in Hypertrophic Cardiomyopathy

Hypertrophic cardiomyopathy (HCM) is the most common heritable cardiovascular disease. A recent study showed that male KLF10-encoded TGFβ Inducible Early Gene-1 knock-out mice (TIEG(-/-)) develop HCM with 13-fold up-regulation of PTTG1-encoded pituitary tumor-transforming gene 1. We hypothesized TIE...

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Detalhes bibliográficos
Main Authors: Bos, J. Martijn, Subramaniam, Malayannan, Hawse, John R., Christiaans, I., Rajamannan, Nalini M, Maleszewski, Joseph J., Edwards, William D., Wilde, Arthur A.M., Spelsberg, Thomas C., Ackerman, Michael J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3495561/
https://ncbi.nlm.nih.gov/pubmed/22234868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.24058
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