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The Y402H Variant in the Complement Factor H Gene Affects Incidence and Progression of Age-Related Macular Degeneration: Results from Multi-State Models Applied to the Beaver Dam Eye Study

OBJECTIVE: To investigate the impact of age, sex and the Y402H variant in the complement factor H (CFH) gene on incidence, progression and regression of age-related macular degeneration (AMD) and the impact of these factors and AMD on mortality using multi-state models (MSMs). METHODS: Analyses incl...

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Autori principali: Gangnon, Ronald E., Lee, Kristine E., Klein, Barbara E. K., Iyengar, Sudha K., Sivakumaran, Theru A., Klein, Ronald
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3495559/
https://ncbi.nlm.nih.gov/pubmed/22965593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/archophthalmol.2012.693
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