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Monoclonal antibody against a 250,000-dalton glycoprotein of Epstein-Barr virus identifies a membrane antigen and a neutralizing antigen.

An antibody-secreting hybrid cell line was produced by fusion of mouse myeloma cells with splenocytes from mice immunized with virions of the B95-8 strain of Epstein-Barr Virus (EBV). The monoclonal IgG antibody was shown to have anti-EBV activity by the following criteria: (i) It reacted with the m...

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Autores principales: Hoffman, G J, Lazarowitz, S G, Hayward, S D
Formato: Artigo
Lenguaje:Inglês
Publicado: 1980
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC349530/
https://ncbi.nlm.nih.gov/pubmed/6248876
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