Piperlongumine inhibits atherosclerotic plaque formation and vascular smooth muscle cell proliferation by suppressing PDGF receptor signaling

Piperlongumine (piplartine, PL) is an alkaloid found in the long pepper (Piper longum L.) and has well-documented anti-platelet aggregation, anti-inflammatory, and anti-cancer properties; however, the role of PL in prevention of atherosclerosis is unknown. We evaluated the anti-atherosclerotic poten...

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Main Authors: Son, Dong Ju, Kim, Soo Yeon, Han, Seong Su, Kim, Chan Woo, Kumar, Sandeep, Park, Byeoung Soo, Lee, Sung Eun, Yun, Yeo Pyo, Jo, Hanjoong, Park, Young Hyun
Format: Artigo
Sprog:Inglês
Udgivet: 2012
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3495231/
https://ncbi.nlm.nih.gov/pubmed/22995306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2012.09.061
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