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Influence of Statins locally applied from orthopedic implants on osseous integration

BACKGROUND: Simvastatin increases the expression of bone morphogenetic protein 2 (BMP-2) in osteoblasts, therefore it is important to investigate the influence of statins on bone formation, fracture healing and implant integration. The aim of the present study was to investigate the effect of Simvas...

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Detalhes bibliográficos
Main Authors: Pauly, Stephan, Back, David A, Kaeppler, Kathrin, Haas, Norbert P, Schmidmaier, Gerhard, Wildemann, Britt
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3495199/
https://ncbi.nlm.nih.gov/pubmed/23102098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2474-13-208
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