Toxicology, biodistribution and shedding profile of a recombinant measles vaccine vector expressing HIV-1 antigens, in cynomolgus macaques

As a new human immunodeficiency virus type 1 (HIV-1) vaccine approach, the live-attenuated measles virus (MV) Schwarz vaccine strain was genetically engineered to express the F4 antigen (MV1-F4). F4 is a fusion protein comprising HIV-1 antigens p17 and p24, reverse transcriptase and Nef. This study...

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Detalhes bibliográficos
Main Authors: Lorin, Clarisse, Segal, Lawrence, Mols, Johann, Morelle, Danielle, Bourguignon, Patricia, Rovira, Olga, Mettens, Pascal, Silvano, Jérémy, Dumey, Nicolas, Le Goff, Frédérick, Koutsoukos, Marguerite, Voss, Gerald, Tangy, Frédéric
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2012
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3495096/
https://ncbi.nlm.nih.gov/pubmed/22983013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00210-012-0793-4
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