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Force measurements on cargoes in living cells reveal collective dynamics of microtubule motors

Many cellular cargoes move bidirectionally along microtubules, driven by teams of plus- and minus-end–directed motor proteins. To probe the forces exerted on cargoes during intracellular transport, we examined latex beads phagocytosed into living mammalian macrophages. These latex bead compartments...

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Bibliografiske detaljer
Main Authors: Hendricks, Adam G., Holzbaur, Erika L. F., Goldman, Yale E.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3494964/
https://ncbi.nlm.nih.gov/pubmed/23091040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1215462109
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