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Force measurements on cargoes in living cells reveal collective dynamics of microtubule motors
Many cellular cargoes move bidirectionally along microtubules, driven by teams of plus- and minus-end–directed motor proteins. To probe the forces exerted on cargoes during intracellular transport, we examined latex beads phagocytosed into living mammalian macrophages. These latex bead compartments...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
National Academy of Sciences
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3494964/ https://ncbi.nlm.nih.gov/pubmed/23091040 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1215462109 |
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