IL-10–induced microRNA-187 negatively regulates TNF-α, IL-6, and IL-12p40 production in TLR4-stimulated monocytes

IL-10 is a potent anti-inflammatory molecule that, in phagocytes, negatively targets cytokine expression at transcriptional and posttranscriptional levels. Posttranscriptional checkpoints also represent the specific target of a recently discovered, evolutionary conserved class of small silencing RNA...

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Autors principals: Rossato, Marzia, Curtale, Graziella, Tamassia, Nicola, Castellucci, Monica, Mori, Laura, Gasperini, Sara, Mariotti, Barbara, De Luca, Mariacristina, Mirolo, Massimiliano, Cassatella, Marco A., Locati, Massimo, Bazzoni, Flavia
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2012
Matèries:
PNAS Plus
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3494907/
https://ncbi.nlm.nih.gov/pubmed/23071313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1209100109
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