Regulation of ornithine decarboxylase activity by corticotropin in adrenocortical tumor cell clones: roles of cyclic AMP and cyclic AMP-dependent protein kinase.

In Y1 adrenocortical tumor cells, corticotropin (ACTH), cyclic AMP, and 8-bromoadenosine 3',5'-monophosphate (8BrcAMP) stimulated ornithine decarboxylase activity (L-ornithine carboxy-lyase, EC 4.1.1.17) and steroidogenesis. The concentrations required for half-maximal activation of ornith...

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Publicado en:Proc Natl Acad Sci U S A
Autores principales: Kudlow, J E, Rae, P A, Gutmann, N S, Schimmer, B P, Burrow, G N
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 1980
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Research Article
Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC349485/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6248865/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.77.5.2767
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