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Retrocyclin inhibits Gardnerella vaginalis biofilm formation and toxin activity

BACKGROUND: Retrocyclins are cyclic antimicrobial peptides that have been shown to be both broadly active and safe in animal models. RC-101, a synthetic retrocyclin, targets important human pathogens and is a candidate vaginal microbicide. Its activity against microbes associated with bacterial vagi...

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Autores principales: Hooven, Thomas A., Randis, Tara M., Hymes, Saul R., Rampersaud, Ryan, Ratner, Adam J.
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3494843/
https://ncbi.nlm.nih.gov/pubmed/22855857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dks305
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