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Epidermal growth factor-induced down-regulation of receptor does not occur in HeLa cells grown in defined medium.

125I-Labeled epidermal growth factor (EGF) binds to HeLa cells in culture under completely defined conditions in a specific and saturable manner. When the cultures are maintained in serum, all the reported phenomena of down-regulation occur. In contrast, in cultures maintained in serum-free hormone-...

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Autors principals: Wolfe, R A, Wu, R, Sato, G H
Format: Artigo
Idioma:Inglês
Publicat: 1980
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC349478/
https://ncbi.nlm.nih.gov/pubmed/6248863
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