Epidermal growth factor-induced down-regulation of receptor does not occur in HeLa cells grown in defined medium.
125I-Labeled epidermal growth factor (EGF) binds to HeLa cells in culture under completely defined conditions in a specific and saturable manner. When the cultures are maintained in serum, all the reported phenomena of down-regulation occur. In contrast, in cultures maintained in serum-free hormone-...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1980
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC349478/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6248863/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.77.5.2735 |
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