Expression of MHC Class I on breast cancer cells correlates inversely with HER2 expression

HER2 is a promising target for immunotherapeutic interventions with T cell-based approaches since it is amplified and overexpressed in 20–30% of breast cancers. However, several previous studies including ours showed that HER2-overexpressing tumors may escape cytotoxic T lymphocyte-mediated lysis by...

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Bibliografiska uppgifter
Huvudupphovsmän: Inoue, Masayuki, Mimura, Kousaku, Izawa, Shinichiro, Shiraishi, Kensuke, Inoue, Ayako, Shiba, Shugo, Watanabe, Mitsuaki, Maruyama, Takanori, Kawaguchi, Yoshihiko, Inoue, Shingo, Kawasaki, Tomonori, Choudhury, Aniruddha, Katoh, Ryohei, Fujii, Hideki, Kiessling, Rolf, Kono, Koji
Materialtyp: Artigo
Språk:Inglês
Publicerad: Landes Bioscience 2012
Ämnen:
Research Paper
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3494624/
https://ncbi.nlm.nih.gov/pubmed/23170258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.21056
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