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Autophagy on acid

The microenvironment of solid tumors tends to be more acidic (6.5–7.0) than surrounding normal (7.2–7.4) tissue. Chaotic vasculature, oxygen limitation and major metabolic changes all contribute to the acidic microenvironment. We have previously proposed that low extracellular pH (pHe) plays a criti...

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Bibliografische gegevens
Hoofdauteurs: Wojtkowiak, Jonathan W., Gillies, Robert J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Landes Bioscience 2012
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3494602/
https://ncbi.nlm.nih.gov/pubmed/22874557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.21501
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