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A Method for Large-scale Identification of Protein Arginine Methylation

The lack of methods for proteome-scale detection of arginine methylation restricts our knowledge of its relevance in physiological and pathological processes. Here we show that most tryptic peptides containing methylated arginine(s) are highly basic and hydrophilic. Consequently, they could be consi...

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Auteurs principaux: Uhlmann, Thomas, Geoghegan, Vincent L., Thomas, Benjamin, Ridlova, Gabriela, Trudgian, David C., Acuto, Oreste
Format: Artigo
Langue:Inglês
Publié: The American Society for Biochemistry and Molecular Biology 2012
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3494207/
https://ncbi.nlm.nih.gov/pubmed/22865923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M112.020743
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