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Major Histocompatibility Complex Class II(+) Invariant Chain Negative Breast Cancer Cells Present Unique Peptides that Activate Tumor-specific T Cells from Breast Cancer Patients
The major histocompatibility complex (MHC) class II-associated Invariant chain (Ii) is present in professional antigen presenting cells where it regulates peptide loading onto MHC class II molecules and the peptidome presented to CD4(+) T lymphocytes. Because Ii prevents peptide loading in neutral s...
में बचाया:
मुख्य लेखकों: | , , , |
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स्वरूप: | Artigo |
भाषा: | Inglês |
प्रकाशित: |
The American Society for Biochemistry and Molecular Biology
2012
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विषय: | |
ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3494186/ https://ncbi.nlm.nih.gov/pubmed/22942358 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M112.019232 |
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