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Deadly Teamwork: Neural Cancer Stem Cells and the Tumor Microenvironment

Neural cancers display cellular hierarchies with self-renewing tumorigenic cancer stem cells (CSCs) at the apex. Instructive cues to maintain CSCs are generated by both intrinsic networks and the niche microenvironment. The CSC-microenvironment relationship is complex as CSCs can modify their enviro...

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Bibliografiske detaljer
Main Authors: Lathia, Justin D., Heddleston, John M., Venere, Monica, Rich, Jeremy N.
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3494093/
https://ncbi.nlm.nih.gov/pubmed/21549324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2011.04.013
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