Identification and Characterization of the Chaetoviridin and Chaetomugilin Gene Cluster in Chaetomium globosum Reveals Dual Functions of an Iterative Highly-Reducing Polyketide Synthase

We report the identification and characterization of the caz biosynthetic cluster from C. globosum and the characterization of a highly-reducing polyketide synthase (PKS) that acts in both a sequential and convergent manner with a nonreducing PKS to form the chaetomugilin and chaetoviridin azaphilon...

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Bibliographic Details
Main Authors: Winter, Jaclyn M., Sato, Michio, Sugimoto, Satoru, Chiou, Grace, Garg, Neil K., Tang, Yi, Watanabe, Kenji
Format: Artigo
Language:Inglês
Published: 2012
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3494086/
https://ncbi.nlm.nih.gov/pubmed/23072467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja3090498
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