Stromal Adipocyte Enhancer-binding Protein (AEBP1) Promotes Mammary Epithelial Cell Hyperplasia via Proinflammatory and Hedgehog Signaling

Disruption of mammary stromal-epithelial communication leads to aberrant mammary gland development and induces mammary tumorigenesis. Macrophages have been implicated in carcinogenesis primarily by creating an inflammatory microenvironment, which promotes growth of the adjacent epithelial cells. Adi...

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Hlavní autoři: Holloway, Ryan W., Bogachev, Oleg, Bharadwaj, Alamelu G., McCluskey, Greg D., Majdalawieh, Amin F., Zhang, Lei, Ro, Hyo-Sung
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2012
Témata:
Molecular Bases of Disease
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3493957/
https://ncbi.nlm.nih.gov/pubmed/22995915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.404293
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