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Matrix Metalloproteinase 9 (MMP-9)-dependent Processing of βig-h3 Protein Regulates Cell Migration, Invasion, and Adhesion

Cell migration is critically involved in inflammation, cancer, and development. In this study, transforming growth factor-β-induced protein (βig-h3) was identified as a substrate of matrix metalloproteinase-9 (MMP-9) by site-directed mutagenesis. βig-h3 has two cleavage sites with the consensus sequ...

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Detalhes bibliográficos
Main Authors: Kim, Yeon Hyang, Kwon, Hyung-Joo, Kim, Doo-Sik
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3493937/
https://ncbi.nlm.nih.gov/pubmed/23019342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.357863
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