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Interpretation of single and serial measures of HE4 and CA125 in asymptomatic women at high risk for ovarian cancer

BACKGROUND: Human epididymis protein 4 (HE4) is approved for clinical use with CA125 to predict epithelial ovarian cancer (EOC) in women with a pelvic mass or in remission after chemotherapy. Previously reported reference ranges for HE4 are inconsistent. METHODS: We report positivity thresholds yiel...

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Bibliographic Details
Main Authors: Urban, Nicole, Thorpe, Jason, Karlan, Beth Y., McIntosh, Martin W., Palomares, Melanie R., Daly, Mary B., Paley, Pamela, Drescher, Charles W.
Format: Artigo
Language:Inglês
Published: 2012
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3493821/
https://ncbi.nlm.nih.gov/pubmed/22962406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1055-9965.EPI-12-0616
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