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Promoter and histone methylation and p16(INK4A) gene expression in colon cancer
The inactivation of the cyclin-dependent kinase inhibitor p16(INK4A) gene by hypermethylation is observed in numerous types of cancer. New findings indicate that DNA and histone methylation act in concert in gene silencing. In this study, we investigated the methylation status of the p16(INK4A) gene...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
D.A. Spandidos
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3493785/ https://ncbi.nlm.nih.gov/pubmed/23226740 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2012.683 |
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