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Controlled-rate freezer cryopreservation of highly concentrated peripheral blood mononuclear cells results in higher cell yields and superior autologous T-cell stimulation for dendritic cell-based immunotherapy

Availability of large quantities of functionally effective dendritic cells (DC) represents one of the major challenges for immunotherapeutic trials against infectious or malignant diseases. Low numbers or insufficient T-cell activation of DC may result in premature termination of treatment and unsat...

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Detalhes bibliográficos
Main Authors: Buhl, Timo, Legler, Tobias J., Rosenberger, Albert, Schardt, Anke, Schön, Michael P., Haenssle, Holger A.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3493671/
https://ncbi.nlm.nih.gov/pubmed/22527251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-012-1262-0
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