Dioscorea alata Attenuates Renal Interstitial Cellular Fibrosis by Regulating Smad- and Epithelial-Mesenchymal Transition Signaling Pathways

Renal interstitial fibrosis is characterized by increased extracellular matrix (ECM) synthesis. Epithelial-mesenchymal transition (EMT) in kidneys is driven by regulated expression of fibrogenic cytokines such as transforming growth factor-beta (TGF-β). Yam, or Dioscorea alata (DA) is an important h...

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Hlavní autoři: Liu, Shu-Fen, Chang, Shan-Yu, Lee, Tao-Chen, Chuang, Lea-Yea, Guh, Jinn-Yuh, Hung, Chien-Ya, Hung, Tsung-Jen, Hung, Yu-Ju, Chen, Po-Yi, Hsieh, Pei-fang, Yang, Yu-Lin
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2012
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3493576/
https://ncbi.nlm.nih.gov/pubmed/23144821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0047482
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