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Single Cell Analysis of Yeast Replicative Aging Using a New Generation of Microfluidic Device

A major limitation to yeast aging study has been the inability to track mother cells and observe molecular markers during the aging process. The traditional lifespan assay relies on manual micro-manipulation to remove daughter cells from the mother, which is laborious, time consuming, and does not a...

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Autores principales: Zhang, Yi, Luo, Chunxiong, Zou, Ke, Xie, Zhengwei, Brandman, Onn, Ouyang, Qi, Li, Hao
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3493551/
https://ncbi.nlm.nih.gov/pubmed/23144860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0048275
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