Luteolin Induces Carcinoma Cell Apoptosis through Binding Hsp90 to Suppress Constitutive Activation of STAT3

BACKGROUND: Abnormal activity of STAT3 is associated with a number of human malignancies. Hsp90 plays a central role in stabilizing newly synthesized proteins and participates in maintaining the functional competency of a number of signaling transducers involved in cell growth, survival and oncogene...

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Detalhes bibliográficos
Main Authors: Fu, Jin, Chen, Dan, Zhao, Bo, Zhao, Zhihui, Zhou, Jiahong, Xu, Yimiao, Xin, Yinqiang, Liu, Chang, Luo, Lan, Yin, Zhimin
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3493516/
https://ncbi.nlm.nih.gov/pubmed/23145121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0049194
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