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Imbalances between Matrix Metalloproteinases (MMPs) and Tissue Inhibitor of Metalloproteinases (TIMPs) in Maternal Serum during Preterm Labor

BACKGROUND: Matrix metalloproteinases (MMPs) are involved in remodeling of the extracellular matrix (ECM) during pregnancy and parturition. Aberrant ECM degradation by MMPs or an imbalance between MMPs and their tissue inhibitors (TIMPs) have been implicated in the pathogenesis of preterm labor, how...

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Detalhes bibliográficos
Main Authors: Tency, Inge, Verstraelen, Hans, Kroes, Ivo, Holtappels, Gabriële, Verhasselt, Bruno, Vaneechoutte, Mario, Verhelst, Rita, Temmerman, Marleen
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3493509/
https://ncbi.nlm.nih.gov/pubmed/23145060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0049042
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