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Bromodomain Protein Brd4 Plays a Key Role in Merkel Cell Polyomavirus DNA Replication
Merkel cell polyomavirus (MCV or MCPyV) is the first human polyomavirus to be definitively linked to cancer. The mechanisms of MCV-induced oncogenesis and much of MCV biology are largely unexplored. In this study, we demonstrate that bromodomain protein 4 (Brd4) interacts with MCV large T antigen (L...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Public Library of Science
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3493480/ https://ncbi.nlm.nih.gov/pubmed/23144621 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003021 |
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