Notch-Mediated Suppression of TSC2 Expression Regulates Cell Differentiation in the Drosophila Intestinal Stem Cell Lineage

Epithelial homeostasis in the posterior midgut of Drosophila is maintained by multipotent intestinal stem cells (ISCs). ISCs self-renew and produce enteroblasts (EBs) that differentiate into either enterocytes (ECs) or enteroendocrine cells (EEs) in response to differential Notch (N) activation. Var...

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Detaylı Bibliyografya
Asıl Yazarlar: Kapuria, Subir, Karpac, Jason, Biteau, Benoit, Hwangbo, DaeSung, Jasper, Heinrich
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2012
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3493453/
https://ncbi.nlm.nih.gov/pubmed/23144631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003045
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