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Notch-Mediated Suppression of TSC2 Expression Regulates Cell Differentiation in the Drosophila Intestinal Stem Cell Lineage

Epithelial homeostasis in the posterior midgut of Drosophila is maintained by multipotent intestinal stem cells (ISCs). ISCs self-renew and produce enteroblasts (EBs) that differentiate into either enterocytes (ECs) or enteroendocrine cells (EEs) in response to differential Notch (N) activation. Var...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Kapuria, Subir, Karpac, Jason, Biteau, Benoit, Hwangbo, DaeSung, Jasper, Heinrich
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2012
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3493453/
https://ncbi.nlm.nih.gov/pubmed/23144631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003045
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