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Development of a rat model of oral small molecule receptor tyrosine kinase inhibitor-induced diarrhea

Orally administered small molecule receptor tyrosine kinase inhibitors (RTKIs) are increasingly common treatments for cancer, both alone and in combination with chemotherapy. However, their side effect profiles and the underlying mechanisms of such are not yet fully elucidated. Management of their m...

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Detalhes bibliográficos
Main Authors: Bowen, Joanne M., Mayo, Bronwen J., Plews, Erin, Bateman, Emma, Stringer, Andrea M., Boyle, Frances M., Finnie, John W., Keefe, Dorothy M.K.
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3493434/
https://ncbi.nlm.nih.gov/pubmed/22895076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.21783
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