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Stage Progression and Neurological Symptoms in Trypanosoma brucei rhodesiense Sleeping Sickness: Role of the CNS Inflammatory Response

BACKGROUND: Human African trypanosomiasis progresses from an early (hemolymphatic) stage, through CNS invasion to the late (meningoencephalitic) stage. In experimental infections disease progression is associated with neuroinflammatory responses and neurological symptoms, but this concept requires e...

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Bibliografiske detaljer
Main Authors: MacLean, Lorna, Reiber, Hansotto, Kennedy, Peter G. E., Sternberg, Jeremy M.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3493381/
https://ncbi.nlm.nih.gov/pubmed/23145191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0001857
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