RNA polymerase I-driven reverse genetics system for enterovirus 71 and its implications for vaccine production

BACKGROUND: Enterovirus 71 (EV71) is a virus that causes from mild hand, foot and mouth disease (HFMD) to severe neurological complications and deaths in infants and young children. Effective antiviral agents and vaccines against EV71 are not available. However, Vero cell-based chemically inactivate...

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Bibliographic Details
Main Authors: Meng, Tao, Kiener, Tanja K, Kwang, Jimmy
Format: Artigo
Language:Inglês
Published: BioMed Central 2012
Subjects:
Methodology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3493273/
https://ncbi.nlm.nih.gov/pubmed/23072515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-9-238
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