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“Shaping” of cell signaling via AKAP-tethered PDE4D: Probing with AKAR2-AKAP5 biosensor

BACKGROUND: PKA, a key regulator of cell signaling, phosphorylates a diverse and important array of target molecules and is spatially docked to members of the A-kinase Anchoring Protein (AKAP) family. AKAR2 is a biosensor which yields a FRET signal in vivo, when phosphorylated by PKA. AKAP5, a promi...

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書誌詳細
主要な著者: Koçer, Salih S, Wang, Hsien-yu, Malbon, Craig C
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3493269/
https://ncbi.nlm.nih.gov/pubmed/22583680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-2187-7-4
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