Evaluation of an [(18)F]AlF-NOTA Analog of Exendin-4 for Imaging of GLP-1 Receptor in Insulinoma

Introduction: The GLP-1 receptor plays an important role in glucose homeostasis and thus is a very important target for diabetes therapy. The receptor is also overexpressed in insulinoma, a tumor of pancreatic beta-cells. We previously evaluated two fluorine-18-labeled analogs of exendin-4 prepared...

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Main Authors: Kiesewetter, Dale O., Guo, Ning, Guo, Jinxia, Gao, Haokao, Zhu, Lei, Ma, Ying, Niu, Gang, Chen, Xiaoyuan
Format: Artigo
Jezik:Inglês
Izdano: Ivyspring International Publisher 2012
Teme:
Research Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3493201/
https://ncbi.nlm.nih.gov/pubmed/23139727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.5276
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