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The Role of Endoplasmic Reticulum Ca(2+)-Independent Phospholipase A(2)γ in Oxidant-Induced Lipid Peroxidation, Ca(2+) Release, and Renal Cell Death
Oxidant-induced lipid peroxidation and cell death are major components of ischemia/reperfusion and toxicant injury. Our previous studies showed that renal proximal tubular cells (RPTCs) express Ca(2+)-independent phospholipase A(2)γ (iPLA(2)γ) in endoplasmic reticulum (ER) and mitochondria and that...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3493193/ https://ncbi.nlm.nih.gov/pubmed/22584685 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfs175 |
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