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DNA methylation and gene expression: endogenous retroviral genome becomes infectious after molecular cloning.

The Mov-3 substrain of mice carries Moloney murine leukemia virus as a Mendelian gene in its germ line. All mice segregating the Mov-3 locus activate virus and develop viremia and leukemia. The integrated provirus (i.e., Mov-3 locus) was molecularly cloned from Mov-3 liver DNA as a 16.8 kilobase lon...

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Main Authors: Harbers, K, Schnieke, A, Stuhlmann, H, Jähner, D, Jaenisch, R
格式: Artigo
語言:Inglês
出版: 1981
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC349318/
https://ncbi.nlm.nih.gov/pubmed/6950402
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